Predisposition
Are genes responsible for cancer?

A familial predisposition is present in up to 30% of patients with gastrointestinal tumours. Within these cases a distinction is made between hereditary gastrointestinal cancer and familial clustering of gastrointestinal cancer. The former group accounts for about 7–10% of all cases of gastrointestinal cancer. In the latter group the precise genetic causes of the familial predisposition are not yet known.

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