In most instances, evidence of chronic hepatitis C infection, e.g. high liver enzyme levels, is discovered by chance via screening tests performed in association with medical examinations or blood donation.

Diagnostic tests for hepatitis C are divided into three general categories:

1. Liver imaging tests

• Ultrasonography (ultrasound)
• Computed tomography (CT scan)
• Magnetic resonance imaging (MRI)

2. Invasive liver tests

• Liver biopsy