Osteoporosis results from an imbalance between the bone-building
and bone-destroying cells involved in the normal cycle of bone
formation and resorption. The loss of bone mass becomes so severe
that even everyday activities that put a minimal strain on bones
can cause them to fracture.
Lifestyle and nutrition:
smoking, excessive alcohol consumption,
lack of exercise, low body weight, inadequate calcium intake
Diseases and the drugs
used to treat them: chemotherapy,
treatment of thyroid disease, chronic corticosteroid therapy,
diabetes, chronic kidney disease