How is HIV infection/AIDS diagnosed?

Methods of demonstrating the disease:

  • The HIV antibody test determines whether the virus has stimulated the body to produce immune substances, or antibodies. If HIV antibodies are found in the blood, the result is checked by means of a second blood test.
  • The direct virus test, which is based on the polymerase chain reaction (PCR), permits direct qualitative demonstration of the virus. Determination of the amount of virus present in the blood, i.e. the ‘viral burden’, is an aid to reliable monitoring of HIV infection and permits rational use of available therapies.
  • Resistance tests determine which medicines are effective against the virus – an essential precondition for effective treatment.

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